Please say no to this one too.
The FDA just approved Zenrelia as an alternative to Apoquel.
Here are several concerns associated with Zenrelia:
Immune System Suppression: Zenrelia functions as a Janus Kinase (JAK) inhibitor, which means it suppresses certain pathways in the immune system to reduce itching and inflammation. While this can alleviate allergic symptoms, it also diminishes the body’s natural defense mechanisms, potentially increasing susceptibility to infections and other diseases. Notably, neoplastic conditions (both benign and malignant) were observed during clinical studies of Zenrelia.
Vaccination Concerns: The FDA has issued a boxed warning for Zenrelia, highlighting risks related to vaccinations. Dogs receiving Zenrelia are at risk of fatal vaccine-induced disease and inadequate immune response to vaccines. It’s recommended to discontinue Zenrelia for at least 28 days to 3 months prior to vaccination and withhold it for at least 28 days after vaccination. This complicates routine vaccination schedules and may leave dogs vulnerable to preventable diseases.
Side Effects: Common adverse reactions reported with Zenrelia include vomiting, diarrhea, and lethargy. These side effects can affect a dog’s quality of life and may require additional interventions to manage.
Lack of Long-Term Safety Data: Zenrelia has not been evaluated in breeding, pregnant, or lactating dogs, nor has it been tested in combination with other systemic immunosuppressive agents like glucocorticoids or cyclosporine. This lack of comprehensive safety data raises concerns about its use in various canine populations and in conjunction with other treatments.
Holistic Perspective: From a holistic standpoint, it’s crucial to address the root causes of allergic reactions rather than solely managing symptoms through immunosuppressive drugs. Exploring alternative therapies such as dietary modifications, herbal supplements, acupuncture, and environmental changes can often provide relief without the associated risks of medications like Zenrelia.
In summary, while Zenrelia may offer symptom relief for allergic dermatitis in dogs, its potential to suppress the immune system, interfere with vaccinations, and cause side effects warrants careful consideration. A holistic approach that focuses on identifying and addressing underlying causes of allergies may provide a safer and more sustainable path to health for your canine companion.
Basically it is another immunosuppressant that increases same risks for infections etc. This one has issues with vaccines. Can kill an animal vaccinated too closely with a modified live vaccine or make the vaccine ineffective. There is a recommended 28 day to 3 month window around this drug and vaccines.
To date, I have an excellent track record getting dogs off Apoquel successfully. So let’s not even start with the drugs!
Read Why we say no to Apoquel too.
https://welloiledk9.com/health/apoquel-for-dog-allergies