Modified citrus pectin (MCP) is a substance derived from the peel and pulp of citrus fruits, such as oranges, lemons, and grapefruits. Pectin is a type of soluble fiber found in these fruits, and when modified, it can have unique properties and potential health benefits.
MCP is often touted for its potential role in cancer treatment, particularly in inhibiting cancer metastasis. Metastasis is the spread of cancer cells from the original tumor to other parts of the body, which is a significant concern in cancer progression and treatment.
Here’s how MCP may help with cancer metastasis:
- Binding to Galectin-3: Galectin-3 is a protein found in cells that plays a role in cancer progression, including metastasis. Research suggests that MCP can bind to galectin-3, potentially blocking its activity and inhibiting cancer cell adhesion, migration, and invasion.
- Immune System Modulation: MCP may modulate the immune system, enhancing its ability to recognize and attack cancer cells. By boosting immune function, MCP could help in targeting and destroying metastatic cancer cells.
- Anti-inflammatory Properties: Chronic inflammation is associated with cancer progression and metastasis. MCP has been shown to have anti-inflammatory properties, which could help in reducing the inflammatory environment that supports cancer metastasis.
- Chelation of Heavy Metals: Some research suggests that MCP may have chelating properties, meaning it can bind to heavy metals in the body and help remove them. Heavy metals can contribute to cancer development and progression, so reducing their presence may indirectly inhibit metastasis.